guanine nucleotide binding protein (G protein), gamma 7; GTP-binding regulatory protein gamma-7 (GNG7, GNGT7)

Function

• G-gamma, component of G-beta-gamma
• G-beta & G-gamma chains are required for
  • GTPase activity of heterotrimeric G proteins
  • replacement of GDP by GTP
  • G protein-effector interaction

Structure

belongs to the G protein gamma family

Compartment

• cell membrane; lipid-anchor; cytoplasmic side (putative)

Expression

expressed in a variety of tissues

Pathology

• down-regulated in pancreatic cancer

More general terms

• guanine nucleotide binding protein (G protein), gamma subunit

Additional terms

• G-beta/gamma
• G-protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2788
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2788
• OMIM: https://mirror.omim.org/entry/604430
• UniProt: http://www.uniprot.org/uniprot/O60262.html