guanine nucleotide binding protein (G protein), gamma 4; GTP-binding regulatory protein gamma-4 (GNG4, GNGT4)

Function

• G-gamma, component of G-beta-gamma
• G-beta & G-gamma chains are required for
  • GTPase activity of heterotrimeric G proteins
  • replacement of GDP by GTP
  • G protein-effector interaction

Structure

belongs to the G protein gamma family

Compartment

• cell membrane; lipid-anchor; cytoplasmic side (putative)

Expression

• brain, kidney, pancreas, skeletal muscle & faintly in cardiac muscle
• expressed in retina?

More general terms

• guanine nucleotide binding protein (G protein), gamma subunit

Additional terms

• G-beta/gamma
• G-protein

Database

• UniProt: http://www.uniprot.org/uniprot/P50150.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2786
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2786
• OMIM: https://mirror.omim.org/entry/604388