bromodomain-containing protein 3; RING3-like protein (BRD3, KIAA0043, RING3L)

Structure

contains 2 bromo domains

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2

Expression

ubiquitous

Pathology

• chromosomal translocation t(9;15)(q34;q14) involving BRD3 with NUT is found in a rare, aggressive, & lethal carcinoma arising in midline organs of young people
• t(9;15)(q34;q14 produces a BRD3-NUT fusion protein

More general terms

• Bromodomain-containing protein
• nuclear protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8019
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8019
• OMIM: https://mirror.omim.org/entry/601541
• UniProt: http://www.uniprot.org/uniprot/Q15059.html