pygopus homolog 2 (PYGO2)

Function

• role in signal transduction through the Wnt pathway
• binds to BCL9 via the PHD-type Zn+2 finger motif, & becomes part of the nuclear beta-catenin/TCF complex

Structure

contains 1 PHD-type Zn+2 finger

Compartment

nucleus (probable)

More general terms

• pygopus homolog
• phosphoprotein
• zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=90780
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:90780
• OMIM: https://mirror.omim.org/entry/606903
• UniProt: http://www.uniprot.org/uniprot/Q9BRQ0.html