clathrin light chain A; Lca (CLTA)

Function

• clathrin light chain
• clathrin is the major protein of the polyhedral coat of coated pits & vesicles
• clathrin coats are formed from molecules containing 3 heavy chains & 3 light chains
• interacts with CALY; the interaction stimulates clathrin self-assembly & clathrin-mediated endocytosis

Compartment

• cytoplasmic vesicle membrane
• peripheral membrane protein; cytoplasmic side
• coated pit
• cytoplasmic face of coated pits & vesicles

Alternative splicing

named isoforms=3

More general terms

• clathrin light chain

Additional terms

• clathrin (triskelion)

Database

• UniProt: http://www.uniprot.org/uniprot/P09496.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1211
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1211
• OMIM: https://mirror.omim.org/entry/118960