phosphatase-2A 72/130 kD regulatory subunit B (PP2A, subunit B, B-PR72/PR130; PP2A, subunit B, B72/B130 isoforms; PP2A, subunit B, PR72/PR130 isoforms; PP2A, subunit B, R3 isoform, PPP2R3A, PPP2R3)

Function

• B regulatory subunit might modulate substrate selectivity & catalytic activity, & also might direct the localization of the catalytic enzyme to a particular subcellular compartment

Structure

contains 2 EF-hand domains

Alternative splicing

named isoforms=2, (72 & 139 kD)

Expression

• expressed in heart, brain, placenta, lung, muscle & kidney

More general terms

• phosphatase-2A B subunit

More specific terms

• phosphatase-2A 130 kD regulatory subunit B
• phosphatase-2A 72 kD regulatory subunit B

Additional terms

• phosphatase-2A (ceramide-activated protein phosphatase)

Database

• UniProt: http://www.uniprot.org/uniprot/Q06190.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5523
• OMIM: https://mirror.omim.org/entry/604944