laminin gamma-3 (laminin 12 gamma 3, LAMC3)

Function

• laminin gamma
• subunit of laminin-12

Structure

• the alpha-helical domains I & II are thought to interact with other laminin chains to form a coiled coil structure
• domain IV is globular
• contains 11 laminin EGF-like domains
• contains 1 laminin IV type A domain
• contains 1 laminin N-terminal domain

Compartment

• secreted, extracellular space, extracellular matrix
• basement membrane

Expression

broadly expressed in skin, heart

More general terms

• laminin-gamma (laminin B2)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1031
• OMIM: https://mirror.omim.org/entry/604349
• UniProt: http://www.uniprot.org/uniprot/Q9Y6N6.html