laminin alpha-5 (laminin A5, LAMA5, KIAA0533, KIAA1907)

Function

• laminin-alpha

Structure

• domain G is globular & is part of the major cell-binding site located in the long arm of the laminin heterotrimer
• contains 22 laminin EGF-like domains
• contains 5 laminin G-like domains
• contains 1 laminin IV type A domain
• contains 1 laminin N-terminal domain

Compartment

• secreted, extracellular space, extracellular matrix
• basement membrane, major component

Expression

• expressed in heart, lung, kidney, skeletal muscle, pancreas, retina & placenta
• little or no expression in brain & liver

More general terms

• laminin-alpha (laminin A)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3911
• OMIM: https://mirror.omim.org/entry/601033
• UniProt: http://www.uniprot.org/uniprot/O15230.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3911