laminin alpha-1 (laminin-A1, LAMA1)
Jump to navigation
Jump to search
Function
- subunit of laminin-1 (EHS laminin) & laminin-3 (S-laminin)
Structure
- alpha-helical domains I & II are thought to interact with other laminin chains to form a coiled coil structure
- domains VI, IV & G are globular
- contains 17 laminin EGF-like domains
- contains 5 laminin G-like domains
- contains 2 laminin IV type A domains
- contains 1 laminin N-terminal domain
Compartment
- secreted, extracellular space, extracellular matrix
- basement membrane, major component
More general terms
References
- ↑ Molecular Cell Biology (2nd ed) Darnell J; Lodish H & Baltimore D (eds), Scientific American Books, WH Freeman, NY 1990, pg 920
- ↑ Schachner M, Martini R. Glycans and the modulation of neural-recognition molecule function. Trends Neurosci. 1995 Apr;18(4):183-91. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7539963
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=284217
- ↑ UniProt http://www.uniprot.org/uniprot/P25391.html