G-protein-signaling modulator 3 (activator of G-protein signaling 4, protein G18, G18.1b, GPSM3, AGS4, C6orf9, G18)

Function

• regulates the activation of Gi alpha proteins

Structure

• contains 3 GoLoco domains
• GoLoco 1 &/or GoLoco 3 domains exhibit GDI activity towards GDP-bound Gi alpha protein, the GoLoco 2 domain does not

Compartment

cytoplasm

Expression

expressed in heart, placenta, lung & liver

More general terms

• G-protein-signaling modulator (GPSM)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9Y4H4.html