double homeobox protein 4 (DUX4, double homeobox protein 10, DUX10)

Function

• transcriptional regulation (putative)

Compartment

• nucleus
• actively transported through the nuclear pore complex

Expression

does not seem to be expressed in normal muscle

Pathology

• defects in DUX4 may be the cause of facioscapulohumeral muscular dystrophy

More general terms

• double homeobox protein

Database

• OMIM: https://mirror.omim.org/entry/158900
• OMIM: https://mirror.omim.org/entry/606009
• UniProt: http://www.uniprot.org/uniprot/Q9UBX2.html