ubiquilin-2; chap1; DSK2 homolog; protein linking IAP with cytoskeleton 2; PLIC-2; hPLIC-2; ubiquitin-like product chap1/Dsk2 (UBQLN2, N4BP4, PLIC2, HRIHFB2157)

Function

• increases the t1/2 of proteins destined to be degraded by the proteasome
• colocalizes with proteasome
• interacts with the 19S proteasome subunit

Structure

• contains 1 UBA domain
• contains 1 ubiquitin-like domain

Compartment

• cytoplasm, nucleus
• colocalizes with the proteasome
• associated with fibers in mitotic cells

Expression

• highly expressed in mitotic cells from metaphase to telophase
• expression in non-mitotic cells is very low

More general terms

• ubiquilin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29978
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29978
• OMIM: https://mirror.omim.org/entry/300264
• UniProt: http://www.uniprot.org/uniprot/Q9UHD9.html