vacuolar protein sorting-associated protein 33B (VPS33B, hVPS33B)

Function

• vesicle-mediated protein trafficking to lysosomal compartments
• membrane docking/fusion reactions of late endosomes/lysosomes

Compartment

• late endosomal membrane
• peripheral membrane
• lysosomal membrane

Expression

-ubiquitous

• highly expressed in testis -expression in the lung Pathogy:
• defects in VPS33B are the cause of arthrogryposis-renal dysfunction-cholestasis syndrome

More general terms

• vacuolar protein sorting-associated protein (VPS)

Additional terms

• arthrogryposis-renal dysfunction-cholestasis syndrome

Database

• OMIM: https://mirror.omim.org/entry/208085
• OMIM: https://mirror.omim.org/entry/608552
• UniProt: http://www.uniprot.org/uniprot/Q9H267.html