testis-specific Y-encoded protein 2 (testis-specific Y-encoded protein Q1, TSPY2, TSPYQ1)

Function

• may be involved in sperm differentiation & proliferation

Structure

• belongs to the nucleosome assembly protein (NAP) family

Compartment

• cytoplasm (putative)
• nucleus

Pathology

• lies in a chromosomal region that is frequently deleted in infertile males

Polymorphism

• maps to a tandemly repeated region on chromosome Yp11;
• at least one copy is reported originating from Yq
• gene is thought to be present with an inter-individual variation in copy number & between 20 & 60 copies per Y chromosome are expected

More general terms

• testis-specific protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6459
• UniProt: http://www.uniprot.org/uniprot/A6NKD2.html