dual specificity protein phosphatase 14 (MAP kinase phosphatase 6, MKP-1 like protein tyrosine phosphatase, MKP-L, DUSP14)

Function

• role in the inactivation of MAP kinases
• dephosphorylates ERK, JNK & p38 MAP-kinases
• interacts with CD28

protein tyrosine phosphate + H2O
                <-->
protein tyrosine + phosphate

a phosphoprotein + H2O <--> a protein + phosphate

Structure

• belongs to the protein-tyrosine phosphatase family non-receptor class dual specificity subfamily
• contains 1 tyrosine-protein phosphatase domain

More general terms

• dual specificity phosphatase
• mitogen activated protein kinase phosphatase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1107
• OMIM: https://mirror.omim.org/entry/606618
• UniProt: http://www.uniprot.org/uniprot/O95147.html