dual specificity protein phosphatase 3 (vaccinia virus phosphatase VH1-related, VHR, DUSP3)

Function

• dual specificity tyrosine/serine-threonine phosphatase highly specific for MAP kinases

protein tyrosine phosphate + H2O
                  <-->
protein tyrosine + phosphate

phosphoprotein + H2O = a protein + phosphate

Structure

• belongs to the protein-tyrosine phosphatase family non-receptor class dual specificity subfamily
• homology to CL100 phosphatase
• contains 1 tyrosine-protein phosphatase domain

More general terms

• dual specificity phosphatase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1845
• OMIM: https://mirror.omim.org/entry/600183
• UniProt: http://www.uniprot.org/uniprot/P51452.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1845