Ufm1-specific protease 2 (UfSP2, UFSP2, C4orf20)

Function

• thiol protease
• recognizes & hydrolyzes peptide bond at the C-terminal Gly of UFM1, an ubiquitin-like modifier protein bound to a number of target proteins
• does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins

Structure

belongs to the peptidase C78 family

More general terms

• cysteine proteinase; thiol proteinase

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NUQ7.html