homeobox protein aristaless-like 3; proline-rich transcription factor ALX3 (ALX3)

Function

• transcriptional regulator with a possible role in patterning of mesoderm during development (putative)

Structure

• belongs to the paired homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus (putative)

Pathology

• defects in ALX3 are the cause of frontonasal dysplasia type 1

More general terms

• homeobox protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=257
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:257
• OMIM: https://mirror.omim.org/entry/136760
• OMIM: https://mirror.omim.org/entry/606014
• UniProt: http://www.uniprot.org/uniprot/O95076.html