distal-less homeobox protein-4; homeobox protein DLX-4; beta protein 1; BP1 (DLX4, DLX7, DLX8)

Function

• may play a role in determining the production of hemoglobin S
• may act as a repressor

Structure

• belongs to the distal-less homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus (putative)

Alternative splicing

• named isoforms=3
• additional isoforms seem to exist

Expression

• expressed in leukemia cells & placenta
• expressed in kidney & fetal liver

More general terms

• distal-less homeobox protein (DLX)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1748
• OMIM: https://mirror.omim.org/entry/601911
• UniProt: http://www.uniprot.org/uniprot/Q92988.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1748