ATP-binding cassette, sub-family A (ABC1), member 10

Function

• probable transporter
• role in macrophage lipid homeostasis

Structure

• belongs to the ABC transporter family, ABCA subfamily
  • contains 2 ABC transporter domains

Compartment

membrane

Alternative splicing

named isoforms=5

Expression

• widely expressed
• highly expressed in skeletal muscle, heart, brain & gastrointestinal tract
• down-regulated by cholesterol loading of macrophages

More general terms

• transmembrane 15 protein
• ATP-binding cassette sub-family A (ABC transporter-A, ABCA)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10349
• UniProt: http://www.uniprot.org/uniprot/Q8WWZ4.html