calsequestrin-1; calsequestrin, skeletal muscle isoform; calmitin (CASQ1, CASQ)
Jump to navigation
Jump to search
Function
- high-capacity, moderate affinity, Ca+2-binding protein
- acts as an internal Ca+2 store in muscle
- release of Ca+2 bound to calsequestrin through a Ca+2 release channel triggers muscle contraction
- binds 40-50 Ca+2
- binds laminin
Structure
belongs to the calsequestrin family
Compartment
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P31415.html
- ↑ Wikipedia; Note: calsequestrin entry http://en.wikipedia.org/wiki/calsequestrin
- ↑ OMIM https://mirror.omim.org/entry/114250
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=844
- ↑ Bataille N et al Molecular cloning of human calmitine, a mitochondrial calcium binding protein, reveals identity with calsequestrine. Biochem Biophys Res Commun. 1994 Sep 30;203(3):1477-82. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7945294