nucleoside diphosphate kinase-7 (NDK 7, NDP kinase 7, nm23-H7, NME7)

Function

• major role in the synthesis of nucleoside triphosphates other than ATP
• ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate

ATP + nucleoside diphosphate <--> ADP + nucleoside triphosphate

Cofactor: Mg+2 (putative)

Structure

belongs to the NDK family

More general terms

• nucleoside diphosphate kinase (NDK) or NDP kinase

Database

• UniProt: http://www.uniprot.org/uniprot/Q9Y5B8.html