isopentenyl-diphosphate delta-isomerase 2; isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2 (IDI2)

Function

• catalyzes isomerization of isopentenyl pyrophophosphate to dimethylallyl pyrophosphate in the biosynthesis of cholesterol ,

Cofactor: binds 1 Mg+2 per subunit (putative)

Structure

• belongs to the IPP isomerase type 1 family
• contains 1 nudix hydrolase domain

Compartment

peroxisome

Expression

detected in skeletal muscle

More general terms

• isopentenyl pyrophosphate isomerase

Additional terms

• cholesterol biosynthesis

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=91734
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:91734
• UniProt: http://www.uniprot.org/uniprot/Q9BXS1.html