isopentenyl-diphosphate delta-isomerase 1; isopentenyl pyrophosphate isomerase 1; IPP isomerase 1; IPPI1 (IDI1)

Function

• catalyzes isomerization of isopentenyl pyrophophosphate to dimethylallyl pyrophosphate in the biosynthesis of cholesterol

Cofactor: binds 1 Mg+2 per subunit

Structure

• monomer
• belongs to the IPP isomerase type 1 family
• contains 1 nudix hydrolase domain

Compartment

peroxisome

Alternative splicing

named isoforms=2

More general terms

• isopentenyl pyrophosphate isomerase

Additional terms

• cholesterol biosynthesis

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3422
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3422
• OMIM: https://mirror.omim.org/entry/604055
• UniProt: http://www.uniprot.org/uniprot/Q13907.html