phosphoglucomutase-5 (phosphoglucomutase-related protein, PGM-RP, aciculin, PGM5, PGMRP)

Function

• component of adherens-type cell-cell & cell-matrix junctions
• lacks phosphoglucomutase activity
• interacts with cytoskeletal proteins dystrophin, utrophin

Cofactor: binds 1 Mg+2 per subunit

Compartment

• cell membrane, cell-cell junction, adherens junction

Expression

• expressed in smooth muscle, cardiac muscle > skeletal muscle
• present in other tissues with vascular or smooth muscle component

More general terms

• phosphoglucomutase or glucose phosphomutase

Database

• OMIM: https://mirror.omim.org/entry/600981
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5239
• UniProt: http://www.uniprot.org/uniprot/Q15124.html