alanine-glyoxylate aminotransferase 2, mitochondrial; AGT 2; (R)-3-amino-2-methylpropionate-pyruvate transaminase; beta-ALAAT II; beta-alanine-pyruvate aminotransferase; D-AIBAT (AGXT2, AGT2)

Function

• aminotransferase

L-alanine + glyoxylate = pyruvate + glycine

(R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine

Cofactor: pyridoxal phosphate

Structure

• homotetramer
• belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family

Compartment

• mitochondria

More general terms

• aminotransferase
• mitochondrial protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=64902
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:64902
• OMIM: https://mirror.omim.org/entry/612471
• UniProt: http://www.uniprot.org/uniprot/Q9BYV1.html