uridine diphosphate glucose pyrophosphatase; UDPG pyrophosphatase; UGPPase; nucleoside diphosphate-linked moiety X motif 14; Nudix motif 14 (NUDT14, UGPP)

Function

-..........-

UDP-glucose + H2O  <-->  UMP + glucose 1-phosphate

ADP-ribose  + H2O   <-->  ADP + ribose 5-phosphate

Cofactor: Mg+2

Kinetic parameters:

• pH dependence: optimum pH is 8.0-9.5

Structure

• homodimer
• belongs to the Nudix hydrolase family
• contains 1 nudix hydrolase domain

Compartment

cytoplasm

More general terms

• pyrophosphatase (diphosphohydrolase)
• nucleoside diphosphate-linked moiety X motif

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=256281
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:256281
• OMIM: https://mirror.omim.org/entry/609219
• UniProt: http://www.uniprot.org/uniprot/O95848.html