NG,NG-dimethylarginine dimethylaminohydrolase 2 (dimethylargininase-2, dimethylarginine dimethylaminohydrolase 2, DDAHII, S-phase protein, protein G6a, DDAH2, DDAH, G6A, NG30)

Function

• hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) & N(G)-monomethyl-L-arginine (MMA), inhibitors of NOS (nitric oxide synthase)
• role in nitric oxide generation

N(G),N(G)-dimethyl-L-arginine + H2O  <-->
                                 dimethylamine + L-citrulline

More general terms

• aminohydrolase (deaminase)

Database

• OMIM: https://mirror.omim.org/entry/604744
• UniProt: http://www.uniprot.org/uniprot/O95865.html