UDP-glucuronosyltransferase-2B7 (UDPGT, 3,4- catechol estrogen specific, UDPGTh-2, UGT2B7 UGTB2B9)

Function

• UDPGT is of major importance in the conjugation & subsequent elimination of potentially toxic xenobiotics & endogenous compounds
• specificity for 3,4-catechol estrogens & estriol suggests it may play an important role in regulating their levels

UDP-glucuronate + acceptor
             <-->
UDP + acceptor beta-D-glucuronoside

Structure

belongs to the UDP-glycosyltransferase family

Compartment

microsome

More general terms

• UDP-glucuronosyltransferase-2B (UDPGT-2B)

Database

• UniProt: http://www.uniprot.org/uniprot/P16662.html
• OMIM: https://mirror.omim.org/entry/600068
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7364