membrane-spanning 4-domains subfamily A member 7 (CD20/FC-epsilon-RI-beta family member 4, four-span transmembrane protein 2, CD20 antigen-like 4, MS4A7, 4SPAN2, CD20L4, CFFM4)

Function

• role in signal transduction as a component of a multimeric receptor complex (putative)

Structure

• belongs to the MS4A family

Compartment

membrane

Expression

• ubiquitous expression in normal tissues
• expression higher adult liver, lung, spleen, & heart than in fetal counterparts
• expression is low in promonocytes & higher in mature monocytes

Pathology

• expression is higher in normal tissues than in cancerous tissue or cell lines

More general terms

• transmembrane 4 protein

Additional terms

• CD20; B-lymphocyte antigen CD20; membrane-spanning 4-domains subfamily A member 1; B-lymphocyte surface antigen B1; Leu-16; Bp35 (MS4A1)

Database

• OMIM: https://mirror.omim.org/entry/606502
• UniProt: http://www.uniprot.org/uniprot/Q9GZW8.html