saposin C; co-beta-glucosidase; A1 activator; glucosylceramidase activator; sphingolipid activator protein-2 (SAP-2).
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Function
- saposin-A & saposin-C stimulate hydrolysis of glucosylceramide by beta-glucosylceramidase & galactosylceramide by beta-galactosylceramidase
- saposin-C apparently acts by combining with the enzyme & acidic lipid to form an activated complex, rather than by solubilizing the substrate