DNA helicase INO80 complex homolog 1 (hINO80, INOC1, KIAA1259)

Function

• putative DNA helicase
• binds DNA
• in vitro, has double-stranded DNA-dependent ATPase activity

Structure

• belongs to the SNF2/RAD54 helicase family
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain
• DBINO region is involved in binding to DNA

Compartment

nucleus

Expression

• widely expressed
• expressed in brain, liver & pancreas

* differing accounts of expression

More general terms

• helicase (DNA unwinding protein, DNA untwisting protein)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9ULG1.html