ATP-dependent RNA helicase DDX28; mitochondrial DEAD box protein 28 (DDX28, MDDX28)

Function

• RNA processing or transport (putative)
• RNA & Mg+2-dependent ATPase activity

Structure

• belongs to the DEAD box helicase family
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

• nucleus, mitochondria; transported between these two compartments
• nuclear localization depends on active RNA polymerase 2 transcription

Expression

• expressed in brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary, prostate

More general terms

• helicase (DNA unwinding protein, DNA untwisting protein)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55794
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:55794
• OMIM: https://mirror.omim.org/entry/607618
• UniProt: http://www.uniprot.org/uniprot/Q9NUL7.html