ATP-dependent RNA helicase DDX51; DEAD box protein 51 (DDX51)

Function

• ATP-binding RNA helicase
• biogenesis of 60S ribosomal subunits

Structure

• the Q motif is unique to & characteristic of the DEAD box family of RNA helicases & controls ATP binding & hydrolysis
• belongs to the DEAD box helicase family, DDX51/DBP6 subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

nucleus, nucleolus

More general terms

• helicase (DNA unwinding protein, DNA untwisting protein)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=317781
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:317781
• UniProt: http://www.uniprot.org/uniprot/Q8N8A6.html