ATP-dependent RNA helicase DDX53; cancer-associated gene protein; cancer/testis antigen 26; CT26; DEAD box protein 53; DEAD box protein CAGE (DDX53, CAGE)

Function

• ATP-dependent RNA helicase

Structure

• belongs to the DEAD box helicase family
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain
• contains 1 KH domain

Compartment

nucleus

Expression

• expressed in testis

Pathology

• wide expression in cancer tissues & cancer cell lines

Laboratory

• CAGE Ab in serum/plasma

More general terms

• helicase (DNA unwinding protein, DNA untwisting protein)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=168400
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:168400
• UniProt: http://www.uniprot.org/uniprot/Q86TM3.html