hyaluronan & proteoglycan link protein 2; brain link protein 1 (HAPLN2, BRAL1)

Function

• mediates a firm binding of versican V2 to hyaluronic acid
• may play a pivotal role in formation of the hyaluronan- associated matrix in the central nervous system (CNS) which facilitates neuronal conduction & general structural stabilization
• binds to hyaluronic acid (putative)

Structure

• belongs to the HAPLN family
• contains 1 Ig-like V-type domain
• contains 2 link domains

Compartment

• secreted, extracellular space, extracellular matrix (putative)

Expression

expressed only in adult brain

More general terms

• proteoglycan link protein; cartilage link protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=60484
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:60484
• UniProt: http://www.uniprot.org/uniprot/Q9GZV7.html