esterase-D (ESD, S-formylglutathione hydrolase, FGH)

Function

• serine hydrolase involved in the detoxification of formaldehyde

S-formylglutathione + H2O <--> glutathione + formate

Structure

• homodimer
• belongs to the esterase D family

Compartment

cytoplasm, cytoplasmic vesicle

Polymorphism

2 major electrophoretic isotypes

More general terms

• thiol esterase or thioesterase

Database

• UniProt: http://www.uniprot.org/uniprot/P10768.html
• OMIM: https://mirror.omim.org/entry/133280