casein kinase 1 alpha (CSNK1A1)

Function

• participates in Wnt signaling
• phosphorylates CTNNB1 on Ser-45
• interacts with the Axin complex

Structure

• monomer
• belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family, casein kinase 1 subfamily
• contains 1 protein kinase domain

Compartment

cytoplasm

More general terms

• casein kinase 1

Database

• UniProt: http://www.uniprot.org/uniprot/P48729.html
• OMIM: https://mirror.omim.org/entry/600505
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1452