ubiquitin carboxyl-terminal hydrolase 40; deubiquitinating enzyme 40; ubiquitin thiolesterase 40; ubiquitin-specific-processing protease 40 (USP40)

Function

• may be catalytically inactive
• thiol-dependent hydrolysis of ester, thioester, amide, peptide & isopeptide bonds formed by the C-terminal Gly of ubiquitin

Structure

belongs to the peptidase C19 family

Alternative splicing

named isoforms=2

Expression

broadly expressed

More general terms

• ubiquitin C-terminal hydrolase
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55230
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:55230
• OMIM: https://mirror.omim.org/entry/610570
• UniProt: http://www.uniprot.org/uniprot/Q9NVE5.html