ubiquitin carboxyl-terminal hydrolase 37; deubiquitinating enzyme 37; ubiquitin thiolesterase 37; ubiquitin-specific-processing protease 37 (USP37, KIAA1594)

Function

• thiol-dependent hydrolysis of ester, thioester, amide, peptide & isopeptide bonds formed by the C-terminal Gly of ubiquitin

Structure

• belongs to the peptidase C19 family
• contains 3 UIM (ubiquitin-interacting motif) repeats

Expression

expressed in brain & prostate

More general terms

• ubiquitin C-terminal hydrolase
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57695
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57695
• UniProt: http://www.uniprot.org/uniprot/Q86T82.html