ubiquitin carboxyl-terminal hydrolase 35; deubiquitinating enzyme 35; ubiquitin thiolesterase 35; ubiquitin-specific-processing protease 35 (USP35, KIAA1372)

Function

• thiol-dependent hydrolysis of ester, thioester, amide, peptide & isopeptide bonds formed by the C-terminal Gly of ubiquitin

Structure

belongs to the peptidase C19 family

Alternative splicing

named isoforms=2

Expression

• expressed in testis, pancreas & skeletal muscle

More general terms

• ubiquitin C-terminal hydrolase
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57558
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57558
• UniProt: http://www.uniprot.org/uniprot/Q9P2H5.html