ubiquitin carboxyl-terminal hydrolase 41; deubiquitinating enzyme 41; ubiquitin thiolesterase 41; ubiquitin-specific-processing protease 41 (USP41)
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Function
- may recognize & hydrolyze the peptide bond at the C-terminal Gly of ubiquitin
- role in processing of poly-ubiquitin precursors as well as that of ubiquinated proteins
- thiol-dependent hydrolysis of ester, thioester, amide, peptide & isopeptide bonds formed by the C-terminal Gly of ubiquitin
Structure
belongs to the peptidase C19 family