iroquois-class homeodomain protein IRX-4; homeodomain protein IRXA3; iroquois homeobox protein 4 (IRX4, IRXA3)

Function

• likely to be an important mediator of ventricular differentiation during cardiac development

Structure

• belongs to the TALE/IRO homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus (probable)

Expression

predominantly expressed in cardiac ventricles

More general terms

• Iroquois-class homeodomain protein IRX

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=50805
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:50805
• OMIM: https://mirror.omim.org/entry/606199
• UniProt: http://www.uniprot.org/uniprot/P78413.html