homeobox protein SIX3; sine oculis homeobox homolog 3 (SIX3)

Function

• may be involved in visual system development

Structure

• belongs to the SIX/sine oculis homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

Pathology

• defects in SIX3 are the cause of holoprosencephaly type 2

More general terms

• homeobox protein SIX; sine oculis homeobox homolog (SIX)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6496
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6496
• OMIM: https://mirror.omim.org/entry/157170
• OMIM: https://mirror.omim.org/entry/603714
• UniProt: http://www.uniprot.org/uniprot/O95343.html