arachidonate-12-lipoxygenase 12S type (platelet-type 12 lipoxygenase, ALOX12)

Function

• leukotrienes biosynthesis
• oxygenase & 14,15-leukotriene A4 synthase activity Cofactor Fe+2

Structure

• belongs to the lipoxygenase family
• contains 1 PLAT domain

Compartment

cytoplasm

More general terms

• 12-lipoxygenase; arachidonate-12-lipoxygenase

Additional terms

• lipoxygenase cascade

Database

• UniProt: http://www.uniprot.org/uniprot/P18054.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:239
• OMIM: https://mirror.omim.org/entry/152391
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=239