liprin-beta-2; protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; PTPRF-interacting protein-binding protein 2 (PPFIBP2)

Function

• may regulate disassembly of focal adhesions
• does not bind receptor-like tyrosine phosphatases type 2A
• forms homodimers & heterodimers (putative)

Structure

• the N-terminal coiled coil regions mediate homodimerization preferentially & heterodimerization type beta/beta
• the C-terminal, non-coiled coil regions mediate heterodimerization type beta/alpha (putative)
• belongs to the liprin family, liprin-beta subfamily
• contains 3 SAM (sterile alpha motif) domains

Expression

widely expressed

More general terms

• liprin-beta

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8495
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8495
• OMIM: https://mirror.omim.org/entry/603142
• UniProt: http://www.uniprot.org/uniprot/Q8ND30.html