methionyl tRNA synthetase (methionine-tRNA ligase, MetRS, MARS, MTRNS)

Function

• component of the multisynthetase complex

ATP + L-methionine + tRNA(Met)
            <-->
AMP + diphosphate + L-methionyl-tRNA(Met)

Structure

• belongs to aminoacyl-tRNA synthetase-1 family
• contains 1 GST-like domain
• contains 1 WHEP-TRS domain

Compartment

cytoplasm (probable)

More general terms

• amino acyl tRNA synthetase-1

Component of

• multisynthetase complex

Database

• OMIM: https://mirror.omim.org/entry/156560
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4141
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4141
• UniProt: http://www.uniprot.org/uniprot/P56192.html