sulfotransferase 1C2; ST1C2; sulfotransferase 1C1; SULT1C#1; humSULTC2 (SULT1C2, SULT1C1)

Function

• catalyzes the sulfate conjugation of many drugs, xenobiotic compounds, hormones, & neurotransmitters
• may be involved in the activation of carcinogenic hydroxylamines
• shows activity towards p-nitrophenol & N-hydroxy-2-acetylaminofluorene (N-OH-2AAF)

Structure

• belongs to the sulfotransferase 1 family

Compartment

cytoplasm

Alternative splicing

named isoforms=2; short, long

Expression

• expressed in adult stomach, kidney & thyroid gland
• expressed in fetal kidney & liver

More general terms

• sulfotransferase 1C

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6819
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6819
• OMIM: https://mirror.omim.org/entry/602385
• UniProt: http://www.uniprot.org/uniprot/O00338.html