glycerate kinase (HBeAg-binding protein 4, GLYCTK, HBEBP4, LP5910)

Function

• converts glycerate to 3-phosphoglycerate ATP + (R)-glycerate <--> ADP + 3-phospho-(R)-glycerate

Structure

belongs to the glycerate kinase type-2 family

Compartment

• isoform 1: cytoplasm
• isoform 2: cytoplasm, mitochondrion

Alternative splicing

named isoforms=7

Expression

widely expressed

Pathology

• defects in GLYCTK are the cause of D-glyceric acidemia

More general terms

• kinase or ATP-phosphotransferase

Database

• OMIM: https://mirror.omim.org/entry/220120
• UniProt: http://www.uniprot.org/uniprot/Q8IVS8.html