ketosamine-3-kinase; fructosamine-3-kinase-related protein; FN3K-RP; FN3K-related protein (FN3KRP)
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Function
- deglycating enzyme
- phosphorylates the 3rd carbon of ketosamines (sugar moiety), psicosamines & ribulosamines, but not fructosamines, on third carbon of the sugar moiety
- protein-bound psicosamine 3-phosphates & ribulosamine 3-phosphates areunstable & decompose under physiological conditions.
- may play a role in freeing proteins from ribulosamines or psicosamines, thus phosphorylation leads to deglycation
Structure
belongs to the fructosamine kinase family
Expression
expressed in erythrocytes